Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis.
OBJECTIVE Sirtuins (SIRTs) play a prominent role in metabolism, apoptosis, aging, inflammation, and epigenetics. Inflammation, apoptosis, and epigenetics are pathogenic issues in rheumatoid arthritis (RA). This study aimed to evaluate SIRT2 and SIRT3 mRNA expressions in patients with RA. MATERIAL AND METHODS Fifty-four patients with RA and 26 healthy controls were enrolled. Disease activity w...
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Sirtuins (Sirt1-7) are nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases/ADP-ribosyltransferases that modulate many metabolic responses affecting aging. Sirtuins expressed in tissues and organs involved in systemic metabolism have been extensively studied. However, the characteristics of sirtuins in the retina, where local energy expenditure changes dynamically in response ...
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ژورنال
عنوان ژورنال: European Journal of Rheumatology
سال: 2017
ISSN: 2147-9720,2148-4279
DOI: 10.5152/eurjrheum.2017.16056